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Faculty Profile: David Williams
Dr.DavidWilliams
Dr. David Williams
For as long as he can remember, David Williams, Associate Professor of Parasitology, has been interested in science, but after living in West Africa for three years with the Peace Corps, he became particularly fascinated with the possibility of combining his interests in biochemistry and the field of tropical medicine. Countries in West Africa are severely infected with a parasitic disease known as schistosomiasis. This disease infects 280 million people in 75 countries throughout the world, with 280,000 people dying from this disease every year. “Having lived in West Africa from 1980-1983, I could have become infected with schisto, and at that time there was only one treatment—a drug, developed in 1917, that had to be taken intravenously and resulted in the death of 10% of its recipients,” thus, the inspiration for Williams’ current research to discover and develop new drugs that will provide other forms of treatment for schistosomiasis or even a vaccine.

Williams’ research focuses on discovering new targets for chemotherapy development in order to kill the parasite but not the person. One project that Williams has been working on for the past seven years with other researchers is the sequencing of the genome or genetic material of the parasite. Now that this sequence is available, researchers are able to compare the parasite and human genomes in order to find differences to exploit. Another interesting project Williams has been working on is discovering why the parasite has and uses what looks to be a gene from its mammalian host and determining how the parasite obtained this gene in the first place.

Along with research, Williams enjoys working with students, technicians, and postdocs in his research lab. He believes that hands-on experience can sometimes be the best teacher. Williams also enjoys teaching his classes like Parasitology and Genomics and Bioinformatics. Because these courses are somewhat obscure or very new, it is “easy to gauge how much students are learning and the information is useful and interesting.” Williams finds it extremely important to pass on the social aspects of science and research as well: “It is all about education, but how can you tell someone in a third world country who has to gather wood to make a fire in order to boil water that all water must be boiled before it can be used at all? It is just like educating Americans about cardiovascular disease. Even though people know the risk is there, they continue to eat unhealthy things and ignore exercise.”

Williams has a wife and two children--a first-year student in college and a sophomore in high school. After work, Williams loves to garden. He even has a small orchard that he tends. Williams is also affiliated with the Land Connection, an organization that is devoted to creating healthy farms, healthy food, and healthy communities.

Williams joined Illinois State’s Department of Biological Sciences in 1995 as an Assistant Professor of Parasitology and Adjunct Professor of Chemistry. Before coming to Illinois State, he was a Postdoctoral Fellow at New York State Agriculture Experiment Station at Cornell University and Institut Pasteur Lille in France. He holds a Ph.D. in Biochemistry from the University of Illinois-Urbana as well as a B.S. in Biochemistry from Cornell University in New York. While at Illinois State University Williams has received over $1 million in research funding from such places as the National Institutes of Health and the World Health Organization.



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